Cognition/Mood

Bacopa monnieri

Ayurvedic herb used for memory and attention, with modest evidence for adults seeking long-term cognitive support.

Bacopa monnieri

Bacopa monnieri

56
score
B
evidence
Caution
risk

Proven Benefits

01Improves memory recall
02Improves attention and reaction tim
03May reduce anxiety and stress
04May support working memory
05May improve ADHD symptoms

Chemical Forms

Recommended
  • Standardized Bacopa monnieri extract (45-55% bacosides)
  • Standardized Bacopa monnieri extract (about 20% bacosides)
Avoid
  • Unstandardized whole-herb powder (variable bacoside content)
  • Proprietary nootropic blends without disclosed bacopa dose or bacosides
Expert Note

Most human trials use standardized extracts with declared bacoside content, which makes dosing more reliable. Raw powder and hidden-dose blends can vary widely from batch to batch, making benefits and side effects less predictable.

Protocol

Amount
300 mg
Frequency
Once daily or split into 2 doses
When
With food to reduce GI upset; if it causes sleepiness, take it in the evening.

Condition-Based Dosing

Standardized extract with 45-55% bacosides
300 mg daily for at least 8-12 weeks
Standardized extract with about 20% bacosides
300-450 mg daily for 8-12 weeks

Safety & Limits

Upper Safe Limit
No official UL; 450 mg/day of standardized extract has been studied short term in adults.
Cycling
Safe for continuous use

Contraindications

Pregnancy or breastfeeding — insufficient safety data
Thyroid disease or thyroid medication — possible thyroid-modulating effects, monitor closely
Slow heart rate or beta-blocker use — possible additive heart-rate lowering
Peptic ulcer, IBS, or marked GI sensitivity — may worsen nausea or cramping
Sedatives or anticholinergic drugs — CNS or cholinergic effects may be altered
Updated Invalid Date