howtosupplement
Heart/Inflammation/Weight

Chlorella

Freshwater green microalga studied for modest cholesterol and triglyceride reductions, with emerging evidence for metabolic and inflammatory markers.

Chlorella

Chlorella

50
score
C
evidence
Caution
risk

Proven Benefits

01Lowers LDL cholesterol and triglyce
02May improve fasting blood glucose
03May reduce CRP and inflammation
04May improve antioxidant status
05May lower blood pressure

Chemical Forms

Recommended
  • Broken/cracked cell-wall chlorella
  • Chlorella vulgaris
  • Chlorella pyrenoidosa
Avoid
  • Intact-cell-wall chlorella (poorer digestibility and bioavailability)
Expert Note

Chlorella's tough cell wall limits digestion unless it is broken or cracked, which improves release of intracellular nutrients. Trials usually use processed, broken-cell-wall products because intact cells are less digestible and less bioavailable.

Protocol

Amount
3-6 g
Frequency
Once daily
When
With meals to improve absorption and reduce gastrointestinal upset.

Safety & Limits

Upper Safe Limit
10 g/day (highest dose studied short-term without serious adverse effects)
Cycling
Safe for continuous use

Contraindications

Warfarin or other vitamin K antagonists — high vitamin K can antagonize anticoagulation
Autoimmune disease — theoretical immune stimulation may worsen symptoms
Organ transplant or immunosuppressive therapy — possible immune stimulation may counter therapy
Pregnancy or breastfeeding — insufficient safety data at supplemental doses

Synergies

Omega-3

Both may lower triglycerides through different lipid-lowering pathways, so the effects can be additive.

Avoid Combining With

  • ✕Warfarin or other vitamin K antagonists (high vitamin K intake may blunt anticoagulation)
  • ✕Tacrolimus, cyclosporine, or other immunosuppressants (possible immune stimulation may counter therapy)
Updated Invalid Date