Performance/Weight

Laxogenin

Plant-derived brassinosteroid analog marketed for muscle growth, but human evidence is too limited to show reliable benefits in adults.

Laxogenin

Plant-derived brassinosteroid analog marketed for muscle growth, but human evidence is too limited to show reliable benefits in adults.

score

evidence

Caution

risk

Proven Benefits

01May support lean body mass

02May improve strength output

03May aid exercise recovery

Chemical Forms

Recommended

5α-Hydroxy laxogenin
Laxogenin

Avoid

Unstandardized Smilax extracts (unclear active content)
Proprietary blends (hidden dose and poor transparency)

Expert Note

Commercial products usually use laxogenin or 5α-hydroxy laxogenin, but neither has solid human efficacy data. Standardized single-ingredient products are at least easier to verify than vague plant extracts or proprietary blends with undisclosed amounts.

Protocol

Amount

100-200 mg

Frequency

Once daily

When

Any time of day — timing is unstudied, so consistency matters more than timing.

Safety & Limits

Upper Safe Limit

No established UL; doses above 200 mg/day lack meaningful safety data in humans.

Cycling

No evidence-based protocol exists; if used despite weak evidence, limit to short self-trials of 6-8 weeks rather than continuous use.

Contraindications

Pregnancy or breastfeeding — no human safety data

Liver disease — safety is unclear and multi-ingredient muscle products can be hepatotoxic

Hormone-sensitive conditions — product effects are poorly characterized

Use with other bodybuilding or prohormone products — stacked formulas increase uncertainty and risk

Updated Invalid Date