Immunity/Digestion/Beauty

Monolaurin

Coconut-derived fatty acid ester with broad in vitro antimicrobial activity; human clinical trials for oral supplementation remain sparse.

Monolaurin

Coconut-derived fatty acid ester with broad in vitro antimicrobial activity; human clinical trials for oral supplementation remain sparse.

score

evidence

Caution

risk

Proven Benefits

01May reduce HSV outbreak frequency

02May inhibit gram-positive bacteria

03May support gut pathogen defense

04May reduce Candida overgrowth

05May support acne-prone skin

Chemical Forms

Recommended

Monolaurin (glyceryl monolaurate)
Lauricidin pellets

Avoid

Coconut oil as substitute (lauric acid conversion is variable and inefficient)
Unspecified 'monolaurin complex' blends

Expert Note

Supplemental monolaurin delivers the preformed active monoester directly, whereas coconut oil contains lauric acid that must be enzymatically converted. Conversion efficiency varies widely among individuals, making isolated monolaurin more reliable for therapeutic intent. Avoid proprietary blends that do not state monolaurin concentration.

Protocol

Amount

600-1800 mg

Frequency

Once daily or divided into 2-3 doses

When

With meals to minimize stomach upset

Condition-Based Dosing

Recurrent HSV outbreaks

1500-1800 mg daily in divided doses for 8-12 weeks— Discontinue if no reduction in outbreak frequency after 12 weeks.

General immune or gut support

600-900 mg daily— Start low and titrate to assess tolerance.

Safety & Limits

Upper Safe Limit

No established UL; up to 3 g/day studied without reported toxicity, though long-term safety data are limited

Cycling

Safe for continuous use

Contraindications

Coconut or palm allergy — monolaurin is typically derived from these sources

Pregnancy and breastfeeding — insufficient safety data; avoid unless directed by a clinician

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