Digestion/Immunity/Inflammation

Oregano oil

Concentrated essential oil of Origanum vulgare used primarily for small intestinal bacterial overgrowth and gut dysbiosis.

Oregano oil

Concentrated essential oil of Origanum vulgare used primarily for small intestinal bacterial overgrowth and gut dysbiosis.

score

evidence

Caution

risk

Proven Benefits

01Reduces SIBO symptoms

02May combat intestinal Candida

03May reduce intestinal parasites

04May support immune defense

05May lower inflammatory markers

Chemical Forms

Recommended

Standardized oregano oil (carvacrol)
Emulsified oregano oil softgels

Avoid

Pure undiluted essential oil (caustic)
Non-standardized leaf powder (weak)

Expert Note

Standardized extracts provide 50-85% carvacrol, ensuring consistent antimicrobial potency. Non-standardized leaf powders contain only trace essential oils and lack clinical support. Pure essential oils are highly concentrated and can burn mucous membranes; supplement-grade softgels use diluted, food-safe formulations.

Protocol

Amount

150-300 mg

Frequency

1-2 times daily with meals

When

With food to minimize stomach irritation; divide into two doses if taking more than 150 mg daily.

Safety & Limits

Upper Safe Limit

600 mg/day (highest short-term studied dose; no official UL established)

Cycling

4-6 weeks on, then 2-4 weeks off; repeat only if symptoms return or per clinician guidance.

Contraindications

Pregnancy or breastfeeding — insufficient safety data; avoid unless prescribed

Bleeding disorders or anticoagulant use — theoretical antiplatelet effect

Allergy to Lamiaceae family (mint, basil, thyme, lavender) — cross-reactivity risk

GERD or peptic ulcers — may irritate mucous membranes

Avoid Combining With

✕Probiotics (take 2+ hours apart — may kill beneficial bacteria)
✕Iron supplements (wait 2+ hours — polyphenols may reduce absorption)
✕Anticoagulant medications like warfarin (theoretical bleeding risk)
✕Other strong antimicrobials (additive stomach irritation)

Updated Invalid Date