howtosupplement
Mood/Cognition/Immunity

Selank

Synthetic peptide studied for anxiety and cognitive support, with evidence limited to small Russian clinical trials.

Selank

Selank

38
score
C
evidence
Caution
risk

Proven Benefits

01Reduces anxiety
02May improve cognitive function
03May enhance stress resilience
04May support immune response

Chemical Forms

Recommended
  • Selank acetate (intranasal or injectable)
Avoid
  • Unverified lyophilized powders from unregulated vendors
Expert Note

Selank acetate is the studied form, administered intranasally or subcutaneously in Russian trials. Oral bioavailability is negligible due to peptide degradation. Unregulated powders carry sterility and dosing risks without medical oversight.

Protocol

Amount
250-500 mcg
Frequency
Once or twice daily
When
Intranasal or subcutaneous administration per clinical protocol; not for oral use.

Condition-Based Dosing

Generalized anxiety in research settings
250-500 mcg daily, intranasal or subcutaneous

Safety & Limits

Upper Safe Limit
No established UL; highest studied dose ~500 mcg twice daily (small Russian trials)
Cycling
Safe for continuous use

Contraindications

Pregnancy or breastfeeding — no safety data
Autoimmune disorders — theoretical immunomodulation risk
Severe depression or bipolar disorder — unstudied, avoid without psychiatric oversight

Avoid Combining With

  • ✕Alcohol (unpredictable CNS interaction)
  • ✕Benzodiazepines (potential overlapping sedation — consult clinician)
Updated Invalid Date