Digestion/Immunity/Performance
L-Glutamine
The most abundant amino acid in the body, key for gut health, immune function, and muscle recovery.
L-Glutamine
The most abundant amino acid in the body, key for gut health, immune function, and muscle recovery.
62
B
evidenceSafe
riskProven Benefits
01Supports gut barrier integrity
02Enhances immune function
03Reduces exercise-induced fatigue
04Aids post-workout recovery
05May reduce sugar cravings
06Supports wound healing
Chemical Forms
Recommended
- L-Glutamine (free form)
- Glutamine peptides
Avoid
- D-Glutamine
Expert Note
L-form is bioactive; D-form isn't.
Protocol
Amount
5 g - 10 g
Frequency
daily
When
Empty stomach or post-workout
Condition-Based Dosing
General gut health
5 g daily
Leaky gut / IBS support
5-10 g daily
Athletic recovery
5-10 g post-workout
Clinical / critical illness
20-30 g daily
Safety & Limits
Upper Safe Limit
40 g per day (short-term)
Cycling
Safe for continuous use
Contraindications
Liver disease / cirrhosis
Kidney disease
Reye's syndrome
History of seizures
Active MSG sensitivity
Synergies
Complementary amino acids for gut lining repair
Combined microbiome and barrier support
Both repair the intestinal lining
Avoid Combining With
- ✕High-protein meals (reduce relative need)
- ✕Lactulose
Updated 4/18/2026